Thr729

Site Information
MLkkkQytsIHHGVV SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 448201

In vivo Characterization
Methods used to characterize site in vivo:	mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:	E.coli (bacterial) ( 1 )

Disease / Diagnostics Relevance
Relevant diseases:	Alzheimer's disease ( 2 )

References
1	Hajdú I, Végh BM, Szilágyi A, Závodszky P (2023) Beta-Secretase 1 Recruits Amyloid-Beta Precursor Protein to ROCK2 Kinase, Resulting in Erroneous Phosphorylation and Beta-Amyloid Plaque Formation. Int J Mol Sci 24 37445593 Curated Info
2	Muresan Z, Muresan V (2007) The amyloid-beta precursor protein is phosphorylated via distinct pathways during differentiation, mitosis, stress, and degeneration. Mol Biol Cell 18, 3835-44 17634293 Curated Info