Tyr544

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Home > Phosphorylation Site Page: > Tyr544 - VAV1 (mouse)

Site Information
RGTFyQGyRCYRCRA SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 33373900

In vivo Characterization
Methods used to characterize site in vivo:	immunoprecipitation ( 1 ) , mass spectrometry ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:	leukemia ( 1 ) , T cell leukemia ( 1 )
Relevant cell line - cell type - tissue:	COS (fibroblast) ( 1 ) , Jurkat (T lymphocyte) ( 1 )

Upstream Regulation
Treatments:	antibody ( 1 ) , EGF ( 1 )

Downstream Regulation
Effects of modification on VAV1:	activity, induced ( 1 )

References
1	Barreira M, et al. (2014) The C-Terminal SH3 Domain Contributes to the Intramolecular Inhibition of Vav Family Proteins. Sci Signal 7, ra35 24736456 Curated Info

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