Lys80
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Home > Sumoylation Site Page: > Lys80  -  HDGF (human)

Site Information
FGKPNKRkGFsEGLW   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 3278903

In vivo Characterization
Methods used to characterize site in vivo:
2D analysis ( 3 ) , electrophoretic mobility shift ( 3 ) , mass spectrometry ( 1 , 3 ) , modification-specific antibody ( 3 ) , mutation of modification site ( 3 ) , western blotting ( 3 )
Relevant cell line - cell type - tissue:

Downstream Regulation
Effects of modification on HDGF:
molecular association, regulation ( 3 )
Inhibit interaction with:
DNA ( 3 )

References 

1

Hendriks IA, et al. (2014) Uncovering global SUMOylation signaling networks in a site-specific manner. Nat Struct Mol Biol 21, 927-36
25218447   Curated Info

2

Impens F, Radoshevich L, Cossart P, Ribet D (2014) Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli. Proc Natl Acad Sci U S A 111, 12432-7
25114211   Curated Info

3

Thakar K, et al. (2008) SUMOylation of the hepatoma-derived growth factor negatively influences its binding to chromatin. FEBS J 275, 1411-26
18331345   Curated Info