Ser154
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Home > Phosphorylation Site Page: > Ser154  -  PAK3 (human)

Site Information
VNNQKYMsFTSGDKS   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448123

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , mutation of modification site ( 2 )
Disease tissue studied:
HER2 positive breast cancer ( 1 ) , luminal A breast cancer ( 1 ) , luminal B breast cancer ( 1 )
Relevant cell line - cell type - tissue:
breast ( 1 ) , T lymphocyte-blood ( 2 )

Downstream Regulation
Effects of modification on biological processes:
cytoskeletal reorganization ( 2 )

References 

1

Mertins P, et al. (2016) Proteogenomics connects somatic mutations to signalling in breast cancer. Nature 534, 55-62
27251275   Curated Info

2

Nukada Y, et al. (2006) AILIM/ICOS-mediated elongation of activated T cells is regulated by both the PI3-kinase/Akt and Rho family cascade. Int Immunol 18, 1815-24
17077177   Curated Info