Tyr760
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Home > Phosphorylation Site Page: > Tyr760  -  FGFR3 (human)

Site Information
TVTSTDEyLDLSAPF   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 448117

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 , 2 )
Relevant cell line - cell type - tissue:

Downstream Regulation
Effects of modification on FGFR3:
enzymatic activity, induced ( 1 ) , molecular association, regulation ( 1 )
Effects of modification on biological processes:
cell growth, altered ( 2 )
Induce interaction with:
SH2-B-beta (mouse) ( 1 )

References 

1

Kong M, Wang CS, Donoghue DJ (2002) Interaction of fibroblast growth factor receptor 3 and the adapter protein SH2-B. A role in STAT5 activation. J Biol Chem 277, 15962-70
11827956   Curated Info

2

Hart KC, Robertson SC, Donoghue DJ (2001) Identification of tyrosine residues in constitutively activated fibroblast growth factor receptor 3 involved in mitogenesis, Stat activation, and phosphatidylinositol 3-kinase activation. Mol Biol Cell 12, 931-42
11294897   Curated Info