Ser89
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Home > Phosphorylation Site Page: > Ser89  -  DYNC1I2 (rat)

Site Information
VPPPMSPssKSVstP   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 3195347

In vivo Characterization
Methods used to characterize site in vivo:
2D analysis ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
PKCA (human) ( 1 )
Treatments:
Go_6983 ( 1 )

Downstream Regulation
Effects of modification on DYNC1I2:
intracellular localization ( 1 ) , molecular association, regulation ( 1 )
Effects of modification on biological processes:
cell motility, induced ( 1 ) , endocytosis, induced ( 1 )
Inhibit interaction with:
FAK (human) ( 1 ) , PXN (human) ( 1 ) , dynactin 1 (human) ( 1 )

References 

1

Rosse C, et al. (2012) Binding of dynein intermediate chain 2 to paxillin controls focal adhesion dynamics and migration. J Cell Sci 125, 3733-8
22553211   Curated Info