Ser18
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Home > Phosphorylation Site Page: > Ser18  -  CDC42EP4 (mouse)

Site Information
sVNSkRRsRADLtAE   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 3212334

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 2 , 3 , 4 )
Disease tissue studied:
melanoma skin cancer ( 4 )
Relevant cell line - cell type - tissue:
'fat, brown' ( 3 ) , brain ( 3 ) , heart ( 3 ) , kidney ( 3 ) , liver ( 3 ) , lung ( 3 ) , MEF (fibroblast) [TSC2 (mouse), homozygous knockout] ( 2 ) , skin [mGluR1 (mouse), transgenic, TG mutant mice] ( 4 ) , spleen ( 3 )

References 

1

Mertins P, et al. (2014) Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels. Mol Cell Proteomics 13, 1690-704
24719451   Curated Info

2

Yu Y, et al. (2011) Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling. Science 332, 1322-6
21659605   Curated Info

3

Huttlin EL, et al. (2010) A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143, 1174-89
21183079   Curated Info

4

Zanivan S, et al. (2008) Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry. J Proteome Res 7, 5314-26
19367708   Curated Info