Ser336

Site Information
RKQsKRRsNIFtsRk SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 3209577
Available spectra: 1 CST

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 4 , 5 , 6 )
Disease tissue studied:	lung cancer ( 1 , 2 ) , non-small cell lung cancer ( 1 , 2 ) , non-small cell lung adenocarcinoma ( 1 , 2 )
Relevant cell line - cell type - tissue:	A549 (pulmonary) ( 1 ) , DMS153 (pulmonary) ( 2 ) , HeLa (cervical) ( 4 , 5 , 6 ) , K562 (erythroid) ( 4 ) , lung ( 1 , 2 ) , NCI-H1355 (pulmonary) ( 1 ) , NCI-H1437 (pulmonary) ( 2 ) , NCI-H1792 (pulmonary) ( 1 ) , NCI-H2073 (pulmonary) ( 2 ) , NCI-H209 (pulmonary) ( 2 ) , NCI-H23 (pulmonary) ( 1 ) , NCI-H441 (pulmonary) ( 1 ) , NCI-H838 (pulmonary) ( 2 )

Upstream Regulation
Treatments:	BI2536 ( 5 ) , MLN8054 ( 5 )

References
1	Rikova K, Hall B (2013) CST Curation Set: 20736, 21163, 30158, 30159, 30160; Year: 2013; Biosample/Treatment: cell line, A549, H1355, H23, H441, H1792; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY, p[ST], RXXp[ST], pSQ, p[ST]QG, LXRXXp[ST], p[ST]P Curated Info
2	Rikova K, Hall B (2013) CST Curation Set: 20742, 21169, 30176, 30177, 30178; Year: 2013; Biosample/Treatment: cell line, H838, DMS153, H2073, H209, H1437; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY, p[ST], RXXp[ST], pSQ, p[ST]QG, LXRXXp[ST], p[ST]P Curated Info
3	Shiromizu T, et al. (2013) Identification of missing proteins in the neXtProt database and unregistered phosphopeptides in the PhosphoSitePlus database as part of the Chromosome-centric Human Proteome Project. J Proteome Res 12, 2414-21 23312004 Curated Info
4	Zhou H, et al. (2013) Toward a comprehensive characterization of a human cancer cell phosphoproteome. J Proteome Res 12, 260-71 23186163 Curated Info
5	Kettenbach AN, et al. (2011) Quantitative phosphoproteomics identifies substrates and functional modules of aurora and polo-like kinase activities in mitotic cells. Sci Signal 4, rs5 21712546 Curated Info
6	Dephoure N, et al. (2008) A quantitative atlas of mitotic phosphorylation. Proc Natl Acad Sci U S A 105, 10762-7 18669648 Curated Info