Ser878
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Home > Phosphorylation Site Page: > Ser878  -  MASTL (human)

Site Information
HLtVsGFsL______   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 3209094

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 2 , 3 , 4 , 6 , 7 , 8 , 9 , 10 )
Disease tissue studied:
luminal B breast cancer ( 2 ) , cervical cancer ( 8 ) , cervical adenocarcinoma ( 8 ) , leukemia ( 6 ) , acute myelogenous leukemia ( 6 )
Relevant cell line - cell type - tissue:
breast ( 2 ) , E.coli (bacterial) ( 1 ) , HeLa (cervical) ( 3 , 4 , 10 ) , HeLa S3 (cervical) ( 8 , 9 ) , HeLa_Meta (cervical) ( 7 ) , HeLa_Pro (cervical) ( 7 ) , HeLa_Telo (cervical) ( 7 ) , K562 (erythroid) ( 4 ) , KG-1 (myeloid) ( 6 )

Upstream Regulation
Treatments:
MG132_withdrawal ( 7 )

References 

1

Ocasio CA, et al. (2016) A first generation inhibitor of human Greatwall kinase, enabled by structural and functional characterisation of a minimal kinase domain construct. Oncotarget 7, 71182-71197
27563826   Curated Info

2

Mertins P, et al. (2016) Proteogenomics connects somatic mutations to signalling in breast cancer. Nature 534, 55-62
27251275   Curated Info

3

Sharma K, et al. (2014) Ultradeep human phosphoproteome reveals a distinct regulatory nature of Tyr and Ser/Thr-based signaling. Cell Rep 8, 1583-94
25159151   Curated Info

4

Zhou H, et al. (2013) Toward a comprehensive characterization of a human cancer cell phosphoproteome. J Proteome Res 12, 260-71
23186163   Curated Info

5

Klammer M, et al. (2012) Phosphosignature predicts dasatinib response in non-small cell lung cancer. Mol Cell Proteomics 11, 651-68
22617229   Curated Info

6

Weber C, Schreiber TB, Daub H (2012) Dual phosphoproteomics and chemical proteomics analysis of erlotinib and gefitinib interference in acute myeloid leukemia cells. J Proteomics 75, 1343-56
22115753   Curated Info

7

Dulla K, et al. (2010) Quantitative site-specific phosphorylation dynamics of human protein kinases during mitotic progression. Mol Cell Proteomics 9, 1167-81
20097925   Curated Info

8

Olsen JV, et al. (2010) Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. Sci Signal 3, ra3
20068231   Curated Info

9

Daub H, et al. (2008) Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. Mol Cell 31, 438-48
18691976   Curated Info

10

Dephoure N, et al. (2008) A quantitative atlas of mitotic phosphorylation. Proc Natl Acad Sci U S A 105, 10762-7
18669648   Curated Info