Ser723
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Home > Phosphorylation Site Page: > Ser723  -  Caldesmon (human)

Site Information
WEkGNVFssPtAAGt   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 3194450

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 2 , 3 , 4 , 5 , 6 )
Disease tissue studied:
lung cancer ( 3 ) , non-small cell lung cancer ( 3 ) , ovarian cancer ( 2 )
Relevant cell line - cell type - tissue:
H2009 (pulmonary) ( 3 ) , H2887 (pulmonary) ( 3 ) , HCC1359 (pulmonary) ( 3 ) , HCC2279 (pulmonary) ( 3 ) , HCC4006 (pulmonary) ( 3 ) , HeLa (cervical) ( 1 , 6 ) , HUES-7 ('stem, embryonic') ( 4 ) , LOU-NH91 (squamous) ( 3 ) , NCI-H1568 (pulmonary) ( 3 ) , NCI-H2172 (pulmonary) ( 3 ) , NCI-H460 (pulmonary) ( 3 ) , NCI-H647 (pulmonary) ( 3 ) , ovary ( 2 ) , WM115 (melanocyte) ( 5 )

References 

1

Sharma K, et al. (2014) Ultradeep human phosphoproteome reveals a distinct regulatory nature of Tyr and Ser/Thr-based signaling. Cell Rep 8, 1583-94
25159151   Curated Info

2

Mertins P, et al. (2014) Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels. Mol Cell Proteomics 13, 1690-704
24719451   Curated Info

3

Klammer M, et al. (2012) Phosphosignature predicts dasatinib response in non-small cell lung cancer. Mol Cell Proteomics 11, 651-68
22617229   Curated Info

4

Van Hoof D, et al. (2009) Phosphorylation dynamics during early differentiation of human embryonic stem cells. Cell Stem Cell 5, 214-26
19664995   Curated Info

5

Old WM, et al. (2009) Functional proteomics identifies targets of phosphorylation by B-Raf signaling in melanoma. Mol Cell 34, 115-31
19362540   Curated Info

6

Yu LR, et al. (2007) Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra. J Proteome Res 6, 4150-62
17924679   Curated Info