Ser939

Site Information
RRkLDFNsPGGssPV SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 31856385

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 3 , 4 , 6 )
Disease tissue studied:	breast cancer ( 2 ) , lung cancer ( 4 ) , non-small cell lung cancer ( 4 )
Relevant cell line - cell type - tissue:	H2009 (pulmonary) ( 4 ) , H2887 (pulmonary) ( 4 ) , HCC2279 (pulmonary) ( 4 ) , HCC366 (pulmonary) ( 4 ) , HCC78 (pulmonary) ( 4 ) , HCC827 (pulmonary) ( 4 ) , HeLa (cervical) ( 1 , 6 ) , HMLER ('stem, breast cancer') [CXCR4 (human), knockdown] ( 2 ) , HMLER ('stem, breast cancer') ( 2 ) , Jurkat (T lymphocyte) ( 3 ) , LCLC-103H (pulmonary) ( 4 ) , NCI-H2172 (pulmonary) ( 4 )

References
1	Sharma K, et al. (2014) Ultradeep human phosphoproteome reveals a distinct regulatory nature of Tyr and Ser/Thr-based signaling. Cell Rep 8, 1583-94 25159151 Curated Info
2	Yi T, et al. (2014) Quantitative phosphoproteomic analysis reveals system-wide signaling pathways downstream of SDF-1/CXCR4 in breast cancer stem cells. Proc Natl Acad Sci U S A 111, E2182-90 24782546 Curated Info
3	Mertins P, et al. (2013) Integrated proteomic analysis of post-translational modifications by serial enrichment. Nat Methods 10, 634-7 23749302 Curated Info
4	Klammer M, et al. (2012) Phosphosignature predicts dasatinib response in non-small cell lung cancer. Mol Cell Proteomics 11, 651-68 22617229 Curated Info
5	Beli P, et al. (2012) Proteomic Investigations Reveal a Role for RNA Processing Factor THRAP3 in the DNA Damage Response. Mol Cell 46, 212-25 22424773 Curated Info
6	Kettenbach AN, et al. (2011) Quantitative phosphoproteomics identifies substrates and functional modules of aurora and polo-like kinase activities in mitotic cells. Sci Signal 4, rs5 21712546 Curated Info