Ser172
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Home > Phosphorylation Site Page: > Ser172  -  Nedd4-BP3 (mouse)

Site Information
AQLLHALsLDEGGPE   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 3174824

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 2 , 3 , 4 )
Disease tissue studied:
melanoma skin cancer ( 4 )
Relevant cell line - cell type - tissue:
BaF3 ('B lymphocyte, precursor') [JAK3 (human), transfection] ( 1 ) , kidney ( 3 ) , neuron:postsynaptic density-'brain, hippocampus, CA1 region' ( 2 ) , skin [mGluR1 (mouse), transgenic, TG mutant mice] ( 4 )

Upstream Regulation
Treatments:
long-term_potentiation ( 2 )

References 

1

Degryse S, et al. (2017) Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia. Leukemia
28852199   Curated Info

2

Li J, et al. (2016) Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome. Sci Signal 9, rs8
27507650   Curated Info

3

Huttlin EL, et al. (2010) A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143, 1174-89
21183079   Curated Info

4

Zanivan S, et al. (2008) Solid tumor proteome and phosphoproteome analysis by high resolution mass spectrometry. J Proteome Res 7, 5314-26
19367708   Curated Info