Thr231

Site Information
AMBIGUOUS SITES: ognl.NoConversionPossible:
GKLEKNItRGLEEEF SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 31824987

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 )
Disease tissue studied:	leukemia ( 1 ) , acute myelogenous leukemia ( 1 ) , acute erythroid leukemias, including erythroleukemia (M6a) and very rare pure erythroid leukemia (M6b) ( 1 )
Relevant cell line - cell type - tissue:	AML-193 (monocyte) ( 1 ) , HEL (erythroid) ( 1 ) , MV4-11 (macrophage) ( 1 )

Upstream Regulation
Treatments:	JAK_inhibitor_I ( 1 )

References
1	Alcolea MP, et al. (2012) Phosphoproteomic analysis of leukemia cells under basal and drug-treated conditions identifies markers of kinase pathway activation and mechanisms of resistance. Mol Cell Proteomics 11, 453-66 22547687 Curated Info