Lys35

Site Information
RIESYSCkMAGDDKH SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 31094506

In vivo Characterization
Methods used to characterize site in vivo:	mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:	brain cancer ( 1 ) , glioblastoma ( 1 ) , glioma ( 1 )
Relevant cell line - cell type - tissue:	COS7 (fibroblast) ( 1 ) , HEK293T (epithelial) ( 1 ) , U87MG (glial) ( 1 )

Downstream Regulation
Effects of modification on MAF1:	molecular association, regulation ( 1 )
Effects of modification on biological processes:	cell growth, inhibited ( 1 ) , transcription, inhibited ( 1 )
Induce interaction with:	POLR3A (human) ( 1 )

References
1	Rohira AD, Chen CY, Allen JR, Johnson DL (2013) Covalent Small Ubiquitin-like Modifier (SUMO) Modification of Maf1 Protein Controls RNA Polymerase III-dependent Transcription Repression. J Biol Chem 288, 19288-95 23673667 Curated Info