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Site Information |
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DDyHNPGyLVVLPDS SwissProt Entrez-Gene |
Blast this site against: NCBI SwissProt PDB |
Site Group ID: 447760 |
In vivo Characterization | |
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Methods used to characterize site in vivo: | |
Relevant cell line - cell type - tissue: |
Upstream Regulation | |
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Regulatory protein: | |
Treatments: |
Downstream Regulation | |
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Effects of modification on LAT: | |
Induce interaction with: |
References | |
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Xie JJ, et al. (2013) TNFR-associated factor 6 regulates TCR signaling via interaction with and modification of LAT adapter. J Immunol 190, 4027-36
23514740 Curated Info |
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Possemato A (2009) CST Curation Set: 8189; Year: 2009; Biosample/Treatment: cell line, Jurkat/calyculin_A & pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info |
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Houtman JC, et al. (2005) Early phosphorylation kinetics of proteins involved in proximal TCR-mediated signaling pathways. J Immunol 175, 2449-58
16081816 Curated Info |
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Zhang W, et al. (2000) Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling. J Biol Chem 275, 23355-61
10811803 Curated Info |