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Site Information |
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IVHVRGDsEtDLEAL SwissProt Entrez-Gene |
Blast this site against: NCBI SwissProt PDB |
Site Group ID: 484116 |
In vivo Characterization | |
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Methods used to characterize site in vivo: | |
Disease tissue studied: | |
Relevant cell line - cell type - tissue: |
Upstream Regulation | |
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Regulatory protein: | |
Putative in vivo kinases: | |
Treatments: |
Downstream Regulation | |
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Effects of modification on YAP1 iso2: | |
Effects of modification on biological processes: |
References | |
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Nguyen HB, Babcock JT, Wells CD, Quilliam LA (2013) LKB1 tumor suppressor regulates AMP kinase/mTOR-independent cell growth and proliferation via the phosphorylation of Yap. Oncogene 32, 4100-9
23027127 Curated Info |
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Yu FX, et al. (2013) Protein kinase A activates the Hippo pathway to modulate cell proliferation and differentiation. Genes Dev 27, 1223-32
23752589 Curated Info |
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Zhao B, et al. (2010) A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP). Genes Dev 24, 72-85
20048001 Curated Info |
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Zhao B, et al. (2009) Both TEAD-binding and WW domains are required for the growth stimulation and oncogenic transformation activity of yes-associated protein. Cancer Res 69, 1089-98
19141641 Curated Info |