Ser486
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Home > Phosphorylation Site Page: > Ser486  -  GLT1 (rat)

Site Information
sVNVVGDsFGAGIVy   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 3053600

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 1 ) , mutation of modification site ( 1 )
Disease tissue studied:
brain cancer ( 1 ) , glioma ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Treatments:
phorbol_ester ( 1 )

Downstream Regulation
Effects of modification on GLT1:
intracellular localization ( 1 )

References 

1

Kalandadze A, Wu Y, Robinson MB (2002) Protein kinase C activation decreases cell surface expression of the GLT-1 subtype of glutamate transporter. Requirement of a carboxyl-terminal domain and partial dependence on serine 486. J Biol Chem 277, 45741-50
12324450   Curated Info