Lys186
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Home > Acetylation Site Page: > Lys186  -  FOXO4 (human)

Site Information
MLNPEGGkSGkAPRR   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 459042

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , modification-specific antibody ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:
liver cancer ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Treatments:
trichostatin_A ( 1 )

Downstream Regulation
Effects of modification on FOXO4:
activity, inhibited ( 1 )
Effects of modification on biological processes:
transcription, inhibited ( 1 )

References 

1

Fukuoka M, et al. (2003) Negative regulation of forkhead transcription factor AFX (Foxo4) by CBP-induced acetylation. Int J Mol Med 12, 503-8
12964026   Curated Info