Lys287
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Home > Acetylation Site Page: > Lys287  -  RIP140 (mouse)

Site Information
YSREHALkTQNAHQV   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 459036

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry ( 2 , 3 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
COS (fibroblast) ( 1 ) , E.coli (bacterial) ( 3 ) , Sf21 ( 3 )

Upstream Regulation
Treatments:
anacardic acid ( 1 )

Downstream Regulation
Effects of modification on RIP140:
activity, induced ( 1 ) , intracellular localization ( 3 )
Effects of modification on biological processes:
transcription, inhibited ( 1 , 3 )

References 

1

Ho PC, et al. (2008) Modulation of lysine acetylation-stimulated repressive activity by Erk2-mediated phosphorylation of RIP140 in adipocyte differentiation. Cell Signal 20, 1911-9
18655826   Curated Info

2

Mostaqul Huq MD, Gupta P, Wei LN (2008) Post-translational modifications of nuclear co-repressor RIP140: a therapeutic target for metabolic diseases. Curr Med Chem 15, 386-92
18288993   Curated Info

3

Huq MD, Wei LN (2005) Post-translational modification of nuclear co-repressor receptor-interacting protein 140 by acetylation. Mol Cell Proteomics 4, 975-83
15879431   Curated Info

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