Lys292

Site Information
EEENLrkkGEPHHEL SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 458978

In vivo Characterization
Methods used to characterize site in vivo:	[14C] acetate labeling ( 4 ) , mass spectrometry ( 1 , 2 , 3 ) , mass spectrometry (in vitro) ( 4 )
Relevant cell line - cell type - tissue:	liver ( 1 ) , MV4-11 (macrophage) ( 2 ) , SW480 (intestinal) ( 3 )

Upstream Regulation
Treatments:	MS275 ( 2 ) , vorinostat ( 2 )

References
1	Zhao S, et al. (2010) Regulation of cellular metabolism by protein lysine acetylation. Science 327, 1000-4 20167786 Curated Info
2	Choudhary C, et al. (2009) Lysine acetylation targets protein complexes and co-regulates major cellular functions. Science 325, 834-40 19608861 Curated Info
3	Li Y (2007) CST Curation Set: 2376; Year: 2007; Biosample/Treatment: cell line, SW480/untreated &'\|\|' nicotinamide; Disease: colorectal carcinoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: acK Curated Info
4	Wang YH, et al. (2003) Identification and characterization of a novel p300-mediated p53 acetylation site, lysine 305. J Biol Chem 278, 25568-76 12724314 Curated Info