Ser522
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Home > Phosphorylation Site Page: > Ser522  -  CRMP-4 (rat)

Site Information
PAGSTRGsPTRPNPP   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 458800

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 2 , 4 ) , phospho-antibody ( 3 ) , western blotting ( 3 )
Disease tissue studied:
neuroblastoma ( 3 )
Relevant cell line - cell type - tissue:
'brain, brainstem' ( 2 ) , 'brain, cerebellum' ( 2 ) , 'brain, cerebral cortex' ( 2 ) , 'neuron, cortical' ( 3 ) , 293 (epithelial) ( 3 ) , heart ( 2 ) , IEC-6 (epithelial) ( 1 ) , intestine ( 2 ) , kidney ( 2 ) , lung ( 2 ) , SH-SY5Y (neural crest) ( 3 ) , spleen ( 2 ) , stomach ( 2 ) , testis ( 2 ) , thymus ( 2 )

Upstream Regulation
Treatments:
serum ( 1 )

References 

1

Courcelles M, et al. (2013) Phosphoproteome dynamics reveal novel ERK1/2 MAP kinase substrates with broad spectrum of functions. Mol Syst Biol 9, 669
23712012   Curated Info

2

Lundby A, et al. (2012) Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. Nat Commun 3, 876
22673903   Curated Info

3

Cole AR, et al. (2008) Relative Resistance of Cdk5-phosphorylated CRMP2 to Dephosphorylation. J Biol Chem 283, 18227-18237
18460467   Curated Info

4

Cole AR, et al. (2004) GSK-3 phosphorylation of the Alzheimer epitope within collapsin response mediator proteins regulates axon elongation in primary neurons. J Biol Chem 279, 50176-80
15466863   Curated Info