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Site Information |
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MsGTGMRsVtGtPYW SwissProt Entrez-Gene |
Blast this site against: NCBI SwissProt PDB |
Site Group ID: 458796 |
In vivo Characterization | |
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Methods used to characterize site in vivo: | |
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Upstream Regulation | |
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Downstream Regulation | |
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Effects of modification on MEKK3: | |
Effects of modification on biological processes: |
References | |
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Mertins P, et al. (2016) Proteogenomics connects somatic mutations to signalling in breast cancer. Nature 534, 55-62
27251275 Curated Info |
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Sun W, et al. (2010) Phosphorylation of Thr-516 and Ser-520 in the kinase activation loop of MEKK3 is required for lysophosphatidic acid-mediated optimal IkappaB kinase beta (IKKbeta)/nuclear factor-kappaB (NF-kappaB) activation. J Biol Chem 285, 7911-8
20068038 Curated Info |
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Oppermann FS, et al. (2009) Large-scale proteomics analysis of the human kinome. Mol Cell Proteomics 8, 1751-64
19369195 Curated Info |
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Matitau AE, Scheid MP (2008) Phosphorylation of MEKK3 at threonine 294 promotes 14-3-3 association to inhibit nuclear factor kappaB activation. J Biol Chem 283, 13261-8
18308725 Curated Info |
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Zhang D, et al. (2006) Identification of MEKK2/3 serine phosphorylation site targeted by the Toll-like receptor and stress pathways. EMBO J 25, 97-107
16362041 Curated Info |