Tyr294
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Home > Phosphorylation Site Page: > Tyr294  -  Tip60 (human)

Site Information
HPPGNEIyRkGTISF   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 29431804

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
293 (epithelial) ( 1 )

Upstream Regulation
Putative in vivo kinases:
Abl (human) ( 1 )
Kinases, in vitro:
Abl (human) ( 1 )

Downstream Regulation
Effects of modification on Tip60:
acetylation ( 1 ) , enzymatic activity, inhibited ( 1 ) , intracellular localization ( 1 ) , molecular association, regulation ( 1 )
Effects of modification on biological processes:
apoptosis, induced ( 1 ) , cell cycle regulation ( 1 )
Induce interaction with:
Fe65 (human) ( 1 )

References 

1

Shin SH, Kang SS (2013) Phosphorylation of Tip60 Tyrosine 327 by Abl Kinase Inhibits HAT Activity through Association with FE65. Open Biochem J 7, 66-72
24044023   Curated Info

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