Ser151
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Home > Phosphorylation Site Page: > Ser151  -  RGS19 (human)

Site Information
EDyVsILsPkEVSLD   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 447873

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 3 ) , mass spectrometry ( 1 ) , mutation of modification site ( 2 , 3 ) , phosphoamino acid analysis ( 3 )
Disease tissue studied:
colorectal cancer ( 2 ) , colorectal carcinoma ( 2 ) , lung cancer ( 1 ) , non-small cell lung adenocarcinoma ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
ERK2 (human) ( 3 )
Kinases, in vitro:
ERK2 (human) ( 3 )
Treatments:
DRB ( 3 ) , GF109203X ( 3 ) , H-89 ( 3 ) , PD98059 ( 3 ) , SB203580 ( 3 )

Downstream Regulation
Effects of modification on RGS19:
activity, induced ( 2 , 3 )

References 

1

Tsai CF, et al. (2015) Large-scale determination of absolute phosphorylation stoichiometries in human cells by motif-targeting quantitative proteomics. Nat Commun 6, 6622
25814448   Curated Info

2

Pattingre S, Petiot A, Codogno P (2004) Analyses of Galpha-interacting protein and activator of G-protein-signaling-3 functions in macroautophagy. Methods Enzymol 390, 17-31
15488168   Curated Info

3

Ogier-Denis E, Pattingre S, El Benna J, Codogno P (2000) Erk1/2-dependent phosphorylation of Galpha-interacting protein stimulates its GTPase accelerating activity and autophagy in human colon cancer cells. J Biol Chem 275, 39090-5
10993892   Curated Info