Ser700
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Home > Phosphorylation Site Page: > Ser700  -  TRPC3 (human)

Site Information
PPFsLVPsPKsFVyF   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 454431

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 2 ) , mutation of modification site ( 1 , 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
PKCA (human) ( 1 , 2 )
Treatments:
phorbol_ester ( 1 , 2 )

Downstream Regulation
Effects of modification on TRPC3:
activity, inhibited ( 1 , 2 )

References 

1

Kwan HY, Huang Y, Yao X (2006) Protein kinase C can inhibit TRPC3 channels indirectly via stimulating protein kinase G. J Cell Physiol 207, 315-21
16331690   Curated Info

2

Trebak M, et al. (2005) Negative regulation of TRPC3 channels by protein kinase C-mediated phosphorylation of serine 712. Mol Pharmacol 67, 558-63
15533987   Curated Info