Tyr1146
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Home > Phosphorylation Site Page: > Tyr1146  -  MYO6 iso6 (human)

Site Information
APkSVTDyAQQNPAA   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 454905
Available spectra:  1 CST

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 )
Disease tissue studied:
colorectal cancer ( 9 ) , gastric cancer ( 7 , 10 ) , gastric carcinoma ( 10 ) , lung cancer ( 1 , 2 , 3 , 4 , 5 , 6 , 10 ) , non-small cell lung cancer ( 1 , 2 , 3 , 5 , 6 , 8 , 10 ) , non-small cell lung adenocarcinoma ( 1 , 2 , 3 , 4 , 5 , 6 ) , non-small cell large cell lung carcinoma ( 2 , 5 ) , non-small cell squamous cell lung carcinoma ( 4 )
Relevant cell line - cell type - tissue:
A549 (pulmonary) ( 1 ) , Calu-3 (pulmonary) ( 3 ) , DLD1 (intestinal) ( 9 ) , DMS153 (pulmonary) ( 6 ) , HCC15 (pulmonary) ( 4 ) , HCC78 (pulmonary) ( 5 ) , HCC827 (pulmonary) ( 3 ) , LOU-NH91 (squamous) ( 4 ) , lung ( 1 , 2 , 3 , 4 , 5 , 6 ) , MKN-45 (gastric) ( 7 , 10 ) , NCI-H1299 (pulmonary) ( 2 ) , NCI-H1355 (pulmonary) ( 1 ) , NCI-H1437 (pulmonary) ( 6 ) , NCI-H1650 (pulmonary) ( 3 ) , NCI-H1703 (squamous) ( 4 ) , NCI-H1734 (pulmonary) ( 2 ) , NCI-H1781 (pulmonary) ( 5 ) , NCI-H1792 (pulmonary) ( 1 ) , NCI-H1944 (pulmonary) ( 2 ) , NCI-H1975 (pulmonary) ( 3 ) , NCI-H2073 (pulmonary) ( 4 , 6 ) , NCI-H209 (pulmonary) ( 6 ) , NCI-H2106 (pulmonary) ( 3 ) , NCI-H2228 (pulmonary) ( 5 ) , NCI-H23 (pulmonary) ( 1 ) , NCI-H2342 (pulmonary) ( 4 ) , NCI-H3122 (pulmonary) ( 5 ) , NCI-H3255 (pulmonary) ( 8 , 10 ) , NCI-H358 (pulmonary) ( 2 ) , NCI-H441 (pulmonary) ( 1 ) , NCI-H460 (pulmonary) ( 2 ) , NCI-H661 (pulmonary) ( 5 ) , NCI-H838 (pulmonary) ( 6 )

References 

1

Rikova K, Hall B (2013) CST Curation Set: 20736, 21163, 30158, 30159, 30160; Year: 2013; Biosample/Treatment: cell line, A549, H1355, H23, H441, H1792; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY, p[ST], RXXp[ST], pSQ, p[ST]QG, LXRXXp[ST], p[ST]P
Curated Info

2

Rikova K, Hall B (2013) CST Curation Set: 20737, 21164, 30161, 30162, 30163; Year: 2013; Biosample/Treatment: cell line, H1299, H1944, H358, H1734, H460; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY, p[ST], RXXp[ST], pSQ, p[ST]QG, LXRXXp[ST], p[ST]P
Curated Info

3

Rikova K, Hall B (2013) CST Curation Set: 20738, 21165, 30164, 30165, 30166; Year: 2013; Biosample/Treatment: cell line, H1650, HCC827, H1975, Calu-3, H2106; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY, p[ST], RXXp[ST], pSQ, p[ST]QG, LXRXXp[ST], p[ST]P
Curated Info

4

Rikova K, Hall B (2013) CST Curation Set: 20739, 21166, 30167, 30168, 30169; Year: 2013; Biosample/Treatment: cell line, H2342, H2073, Lou-NH91, HCC15, H1703; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY, p[ST], RXXp[ST], pSQ, p[ST]QG, LXRXXp[ST], p[ST]P
Curated Info

5

Rikova K, Hall B (2013) CST Curation Set: 20740, 21167, 30170, 30171, 30172; Year: 2013; Biosample/Treatment: cell line, H2228, H3122, HCC78, H661, H1781; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY, p[ST], RXXp[ST], pSQ, p[ST]QG, LXRXXp[ST], p[ST]P
Curated Info

6

Rikova K, Hall B (2013) CST Curation Set: 20742, 21169, 30176, 30177, 30178; Year: 2013; Biosample/Treatment: cell line, H838, DMS153, H2073, H209, H1437; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY, p[ST], RXXp[ST], pSQ, p[ST]QG, LXRXXp[ST], p[ST]P
Curated Info

7

Rikova K (2012) CST Curation Set: 16137; Year: 2012; Biosample/Treatment: cell line, MKN45/crizotinib; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine (P-Tyr-1000) MultiMab(TM) Rabbit mAb mix Cat#: 8954
Curated Info

8

Rikova K (2012) CST Curation Set: 16138; Year: 2012; Biosample/Treatment: cell line, H3255/iressa; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine (P-Tyr-1000) MultiMab(TM) Rabbit mAb mix Cat#: 8954
Curated Info

9

Organ SL, et al. (2011) Quantitative Phospho-Proteomic Profiling of Hepatocyte Growth Factor (HGF)-MET Signaling in Colorectal Cancer. J Proteome Res 10, 3200-11
21609022   Curated Info

10

Guo A, et al. (2008) Signaling networks assembled by oncogenic EGFR and c-Met. Proc Natl Acad Sci U S A 105, 692-7
18180459   Curated Info