Thr106

Site Information
EEHPVLLtEAPLNPk SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 28702602

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 ) , mass spectrometry (in vitro) ( 3 )
Relevant cell line - cell type - tissue:	3T3 (fibroblast) [KRas (human), transfection] ( 2 ) , C2C12 (myoblast) ( 3 ) , HL-1 (myocyte) [Akt1 (mouse), knockdown, stable lentiviral expression of Akt1 shRNA] ( 1 ) , HL-1 (myocyte) [Akt2 (mouse), knockdown, stable lentiviral expression of Akt2 shRNA] ( 1 ) , HL-1 (myocyte) ( 1 )

References
1	Reinartz M, Raupach A, Kaisers W, Gödecke A (2014) AKT1 and AKT2 induce distinct phosphorylation patterns in HL-1 cardiac myocytes. J Proteome Res 13, 4232-45 25162660 Curated Info
2	Gnad F, et al. (2013) Systems-wide Analysis of K-Ras, Cdc42, and PAK4 Signaling by Quantitative Phosphoproteomics. Mol Cell Proteomics 12, 2070-80 23608596 Curated Info
3	Knight JD, et al. (2012) A novel whole-cell lysate kinase assay identifies substrates of the p38 MAPK in differentiating myoblasts. Skelet Muscle 2, 5 22394512 Curated Info