Ser144
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.7.9
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Ser144  -  CASP9 (human)

Site Information
GDVGALEsLRGNADL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 458346

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 1 )
Relevant cell line - cell type - tissue:
HeLa (cervical) ( 1 ) , U2OS (bone cell) [GR (human)] ( 1 )

Upstream Regulation
Putative in vivo kinases:
PKCZ (human) ( 1 )
Kinases, in vitro:
PKCZ (human) ( 1 )
Treatments:
bisindolylmaleimide ( 1 ) , Go_6976 ( 1 ) , Go_6983 ( 1 ) , H-89 ( 1 ) , LY294002 ( 1 ) , okadaic_acid ( 1 ) , peptide inhibitor ( 1 ) , Ro31-8220 ( 1 ) , SB203580 ( 1 ) , staurosporine ( 1 ) , U0126 ( 1 )

Downstream Regulation
Effects of modification on CASP9:
activity, inhibited ( 1 )
Effects of modification on biological processes:
apoptosis, altered ( 1 )

References 

1

Brady SC, Allan LA, Clarke PR (2005) Regulation of caspase 9 through phosphorylation by protein kinase C zeta in response to hyperosmotic stress. Mol Cell Biol 25, 10543-55
16287866   Curated Info

Developed with grants from  NIH Logo and literature mining with Linguamatics  I2E Logo Creative Commons License PhosphoSite, created by Cell Signaling Technology is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License.

©2003-2024 Cell Signaling Technology, Inc.