Ser492
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Home > Phosphorylation Site Page: > Ser492  -  PTHR (rat)

Site Information
RKARsGsssYsYGPM   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 2853102

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 , 2 ) , western blotting ( 2 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Treatments:
PTH ( 2 )

Downstream Regulation
Effects of modification on PTHR:
activity, inhibited ( 1 ) , receptor internalization, altered ( 2 )

References 

1

Miedlich SU, Abou-Samra AB (2008) Eliminating phosphorylation sites of the parathyroid hormone receptor type 1 differentially affects stimulation of phospholipase C and receptor internalization. Am J Physiol Endocrinol Metab 295, E665-71
18577695   Curated Info

2

Tawfeek HA, Qian F, Abou-Samra AB (2002) Phosphorylation of the receptor for PTH and PTHrP is required for internalization and regulates receptor signaling. Mol Endocrinol 16, 1-13
11773434   Curated Info