Ser484
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Home > Phosphorylation Site Page: > Ser484  -  CD6 (human)

Site Information
DSDsGsDsDYEHYDF   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 28095002

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:
leukemia ( 1 ) , T cell leukemia ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Kinases, in vitro:
CK2A1 (human) ( 1 )
Treatments:
heparin sodium ( 1 ) , phorbol_ester ( 1 )

Downstream Regulation
Effects of modification on CD6:
phosphorylation ( 1 )
Effects of modification on biological processes:
signaling pathway regulation ( 1 )

References 

1

Bonet L, et al. (2013) Identification of functionally relevant phoshorylatable serine clusters in the cytoplasmic region of the human CD6 lymphocyte surface receptor. FEBS Lett 587, 2205-13
23711376   Curated Info