Lys115
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Home > Ubiquitylation Site Page: > Lys115  -  DDX41 (mouse)

Site Information
KQLKEEEkILESVAE   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 27992510

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 )
Disease tissue studied:
fibrosarcoma of soft tissue ( 1 )
Relevant cell line - cell type - tissue:
L929 (fibroblast) ( 1 )

Downstream Regulation
Effects of modification on DDX41:
protein degradation ( 1 )
Effects of modification on biological processes:
transcription, inhibited ( 1 )

References 

1

Zhang Z, et al. (2013) The E3 ubiquitin ligase TRIM21 negatively regulates the innate immune response to intracellular double-stranded DNA. Nat Immunol 14, 172-8
23222971   Curated Info

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