Lys313
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Home > Ubiquitylation Site Page: > Lys313  -  TBX21 (mouse)

Site Information
NAEITQLkIDNNPFA   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 27930806

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , western blotting ( 1 )
Disease tissue studied:
lymphoma ( 1 ) , T cell lymphoma ( 1 )
Relevant cell line - cell type - tissue:
EL-4 (T lymphocyte) ( 1 ) , HEK293T (epithelial) ( 1 ) , T lymphocyte ( 1 )

Downstream Regulation
Effects of modification on TBX21:
molecular association, regulation ( 1 ) , phosphorylation ( 1 ) , protein stabilization ( 1 )
Induce interaction with:
NFAT1 (human) ( 1 )

References 

1

Jang EJ, Park HR, Hong JH, Hwang ES (2013) Lysine 313 of T-box Is Crucial for Modulation of Protein Stability, DNA Binding, and Threonine Phosphorylation of T-bet. J Immunol 190, 5764-70
23616576   Curated Info