Ser1068
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Home > Phosphorylation Site Page: > Ser1068  -  LRRC16 (human)

Site Information
KRDsRKssGFLNLIK   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 27452363

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 , 2 , 4 , 5 )
Disease tissue studied:
breast cancer ( 5 ) , HER2 positive breast cancer ( 1 ) , luminal A breast cancer ( 1 ) , luminal B breast cancer ( 1 ) , breast cancer, surrounding tissue ( 1 ) , breast cancer, triple negative ( 1 ) , acute erythroid leukemias, including erythroleukemia (M6a) and very rare pure erythroid leukemia (M6b) ( 4 ) , acute megakaryoblastic leukemia (M7) ( 4 ) , acute monoblastic leukemia (M5a) or acute monocytic leukemia (M5b) ( 4 ) , acute myeloblastic leukemia, with granulocytic maturation (M2) ( 4 ) , acute myeloblastic leukemia, without maturation (M1) ( 4 ) , lung cancer ( 2 , 5 ) , non-small cell lung cancer ( 5 ) , non-small cell lung adenocarcinoma ( 2 ) , B cell lymphoma ( 4 ) , non-Hodgkin's lymphoma ( 4 ) , multiple myeloma ( 4 )
Relevant cell line - cell type - tissue:
AML-193 (monocyte) ( 4 ) , breast ( 1 ) , BT-20 (breast cell) ( 5 ) , BT-549 (breast cell) ( 5 ) , CMK (megakaryoblast) ( 4 ) , CTS (myeloid) ( 4 ) , DOHH2 ('B lymphocyte, precursor') ( 4 ) , H2009 (pulmonary) ( 5 ) , H2077 (pulmonary) ( 5 ) , H2887 (pulmonary) ( 5 ) , H322 (pulmonary) ( 5 ) , H322M (pulmonary) ( 5 ) , HCC1359 (pulmonary) ( 5 ) , HCC1937 (breast cell) ( 5 ) , HCC2279 (pulmonary) ( 5 ) , HCC366 (pulmonary) ( 5 ) , HCC4006 (pulmonary) ( 5 ) , HCC78 (pulmonary) ( 5 ) , HEL (erythroid) ( 4 ) , HOP62 (pulmonary) ( 5 ) , Kasumi-1 (myeloid) ( 4 ) , KG-1 (myeloid) ( 4 ) , LOU-NH91 (squamous) ( 5 ) , lung ( 2 ) , MCF-7 (breast cell) ( 5 ) , MDA-MB-231 (breast cell) ( 5 ) , MDA-MB-468 (breast cell) ( 5 ) , MV4-11 (macrophage) ( 4 ) , NCI-H1395 (pulmonary) ( 5 ) , NCI-H1568 (pulmonary) ( 5 ) , NCI-H1648 (pulmonary) ( 5 ) , NCI-H2030 (pulmonary) ( 5 ) , NCI-H2172 (pulmonary) ( 5 ) , NCI-H460 (pulmonary) ( 5 ) , NCI-H520 (squamous) ( 5 ) , NCI-H647 (pulmonary) ( 5 ) , OPM-2 (plasma cell) ( 4 ) , P31/FUJ (erythroid) ( 4 ) , PC9 (pulmonary) ( 5 ) , RL ('B lymphocyte, precursor') ( 4 ) , RPMI-8226 (plasma cell) ( 4 ) , SU-DHL-6 (B lymphocyte) ( 4 ) , U266 (plasma cell) ( 4 )

References 

1

Mertins P, et al. (2016) Proteogenomics connects somatic mutations to signalling in breast cancer. Nature 534, 55-62
27251275   Curated Info

2

Schweppe DK, Rigas JR, Gerber SA (2013) Quantitative phosphoproteomic profiling of human non-small cell lung cancer tumors. J Proteomics 91, 286-96
23911959   Curated Info

3

Shiromizu T, et al. (2013) Identification of missing proteins in the neXtProt database and unregistered phosphopeptides in the PhosphoSitePlus database as part of the Chromosome-centric Human Proteome Project. J Proteome Res 12, 2414-21
23312004   Curated Info

4

Casado P, et al. (2013) Phosphoproteomics data classify hematological cancer cell lines according to tumor type and sensitivity to kinase inhibitors. Genome Biol 14, R37
23628362   Curated Info

5

Klammer M, et al. (2012) Phosphosignature predicts dasatinib response in non-small cell lung cancer. Mol Cell Proteomics 11, 651-68
22617229   Curated Info