Arg173

Site Information
SLSQQtPrFNPIMVT SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 27279867
Available spectra: 1 CST

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 )
Disease tissue studied:	lung cancer ( 4 , 5 , 6 , 7 , 8 ) , non-small cell lung cancer ( 4 , 5 , 7 , 8 , 9 ) , non-small cell lung adenocarcinoma ( 4 , 5 , 6 , 7 , 8 ) , non-small cell large cell lung carcinoma ( 5 , 7 ) , non-small cell squamous cell lung carcinoma ( 6 )
Relevant cell line - cell type - tissue:	293 (epithelial) ( 1 ) , A549 (pulmonary) ( 4 ) , DMS153 (pulmonary) ( 8 ) , HCC15 (pulmonary) ( 6 ) , HCC78 (pulmonary) ( 7 ) , HCT116 (intestinal) ( 3 , 10 ) , Jurkat (T lymphocyte) ( 2 ) , LOU-NH91 (squamous) ( 6 ) , lung ( 4 , 5 , 6 , 7 , 8 ) , NCI-H1299 (pulmonary) ( 5 ) , NCI-H1355 (pulmonary) ( 4 ) , NCI-H1437 (pulmonary) ( 8 ) , NCI-H1703 (squamous) ( 6 ) , NCI-H1734 (pulmonary) ( 5 ) , NCI-H1781 (pulmonary) ( 7 ) , NCI-H1792 (pulmonary) ( 4 ) , NCI-H1944 (pulmonary) ( 5 ) , NCI-H2073 (pulmonary) ( 6 , 8 ) , NCI-H209 (pulmonary) ( 8 ) , NCI-H2228 (pulmonary) ( 7 ) , NCI-H23 (pulmonary) ( 4 ) , NCI-H2342 (pulmonary) ( 6 ) , NCI-H3122 (pulmonary) ( 7 , 9 ) , NCI-H358 (pulmonary) ( 5 ) , NCI-H441 (pulmonary) ( 4 ) , NCI-H460 (pulmonary) ( 5 ) , NCI-H661 (pulmonary) ( 7 ) , NCI-H838 (pulmonary) ( 8 ) , T lymphocyte ( 2 )

References
1	Larsen SC, et al. (2016) Proteome-wide analysis of arginine monomethylation reveals widespread occurrence in human cells. Sci Signal 9, rs9 27577262 Curated Info
2	Geoghegan V, et al. (2015) Comprehensive identification of arginine methylation in primary T cells reveals regulatory roles in cell signalling. Nat Commun 6, 6758 25849564 Curated Info
3	Guo A, et al. (2014) Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. Mol Cell Proteomics 13, 372-87 24129315 Curated Info
4	Rikova K (2013) CST Curation Set: 20096; Year: 2013; Biosample/Treatment: cell line, A549, H1355, H23, H441, H1792; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: m1R Antibodies Used to Purify Peptides prior to LCMS: Mono-Methyl Arginine [mme-R] MultiMab(TM) Rabbit mAb mix Cat#: 8015 Curated Info
5	Rikova K (2013) CST Curation Set: 20097; Year: 2013; Biosample/Treatment: cell line, H1299, H1944, H358, H1734, H460; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: m1R Antibodies Used to Purify Peptides prior to LCMS: Mono-Methyl Arginine [mme-R] MultiMab(TM) Rabbit mAb mix Cat#: 8015 Curated Info
6	Rikova K (2013) CST Curation Set: 20099; Year: 2013; Biosample/Treatment: cell line, H2342, H2073, Lou-NH91, HCC15, H1703; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: m1R Antibodies Used to Purify Peptides prior to LCMS: Mono-Methyl Arginine [mme-R] MultiMab(TM) Rabbit mAb mix Cat#: 8015 Curated Info
7	Rikova K (2013) CST Curation Set: 20100; Year: 2013; Biosample/Treatment: cell line, H2228, H3122, HCC78, H661, H1781; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: m1R Antibodies Used to Purify Peptides prior to LCMS: Mono-Methyl Arginine [mme-R] MultiMab(TM) Rabbit mAb mix Cat#: 8015 Curated Info
8	Rikova K (2013) CST Curation Set: 20102; Year: 2013; Biosample/Treatment: cell line, H838, DMS153, H2073, H209, H1437; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: m1R Antibodies Used to Purify Peptides prior to LCMS: Mono-Methyl Arginine [mme-R] MultiMab(TM) Rabbit mAb mix Cat#: 8015 Curated Info
9	Rikova K (2013) CST Curation Set: 18851; Year: 2013; Biosample/Treatment: cell line, H3122/crizotinib, geldanamycin; Disease: -; TMT: Y; Specificities of Antibodies Used to Purify Peptides prior to LCMS: m1R Antibodies Used to Purify Peptides prior to LCMS: Mono-Methyl Arginine [mme-R] MultiMab(TM) Rabbit mAb mix Cat#: 8015 Curated Info
10	Mulhern D (2011) CST Curation Set: 13240; Year: 2011; Biosample/Treatment: cell line, HCT116/untreated; Disease: colorectal carcinoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: m1R Antibodies Used to Purify Peptides prior to LCMS: Mono-Methyl Arginine (Me-R(4)-100) Rabbit mAb Cat#: 8015, PTMScan?(R) Mono-methyl arginine (r) Immunoaffinity Beads Cat#: 8163 Curated Info