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Home > Phosphorylation Site Page: > Ser49  -  PLK1 (human)

Site Information
EVLVDPRsRRRYVRG   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 2715404

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:

Upstream Regulation
Putative in vivo kinases:
PAK1 (human) ( 1 )
Kinases, in vitro:
PAK1 (human) ( 1 )

Downstream Regulation
Effects of modification on PLK1:
enzymatic activity, induced ( 1 )
Effects of modification on biological processes:
cell cycle regulation ( 1 )



Maroto B, et al. (2008) P21-activated kinase is required for mitotic progression and regulates Plk1. Oncogene 27, 4900-8
18427546   Curated Info