Thr75
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Home > Phosphorylation Site Page: > Thr75  -  ATG5 (mouse)

Site Information
IWFEYEGtPLKWHYP   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 27138202

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:
MEF (fibroblast) ( 1 )

Upstream Regulation
Putative in vivo kinases:
P38A (human) ( 1 )
Kinases, in vitro:
P38A (mouse) ( 1 )
Treatments:
SB203580 ( 1 )

Downstream Regulation
Effects of modification on biological processes:
autophagy, inhibited ( 1 )

References 

1

Keil E, et al. (2013) Phosphorylation of Atg5 by the Gadd45β-MEKK4-p38 pathway inhibits autophagy. Cell Death Differ 20, 321-32
23059785   Curated Info