Ser227

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Home > Phosphorylation Site Page: > Ser227 - PINK1 (mouse)

Site Information
MWNISAGsSSEAILS SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 25792200

In vivo Characterization
Methods used to characterize site in vivo:	phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:	endothelial ( 1 )

Upstream Regulation
Regulatory protein:	CAMK1A (human) ( 1 )
Treatments:	Ca(2+) ( 1 ) , pitavastatin ( 1 )

Downstream Regulation
Effects of modification on biological processes:	autophagy, induced ( 1 ) , cell growth, induced ( 1 )

References
1	Yang J, et al. (2022) Pitavastatin activates mitophagy to protect EPC proliferation through a calcium-dependent CAMK1-PINK1 pathway in atherosclerotic mice. Commun Biol 5, 124 35145192 Curated Info

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