Tyr952
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Home > Phosphorylation Site Page: > Tyr952  -  Ret (human)

Site Information
VTLGGNPyPGIPPER   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 447628

In vivo Characterization
Methods used to characterize site in vivo:
[32P] bio-synthetic labeling ( 2 ) , immunoprecipitation ( 2 ) , mutation of modification site ( 1 , 2 ) , phosphoamino acid analysis ( 2 ) , western blotting ( 2 )
Relevant cell line - cell type - tissue:

Downstream Regulation
Effects of modification on Ret:
enzymatic activity, induced ( 1 , 2 )
Effects of modification on biological processes:
cell growth, altered ( 2 )

References 

1

Kato M, et al. (2002) Repair by Src kinase of function-impaired RET with multiple endocrine neoplasia type 2A mutation with substitutions of tyrosines in the COOH-terminal kinase domain for phenylalanine. Cancer Res 62, 2414-22
11956105   Curated Info

2

Iwashita T, et al. (1996) Identification of tyrosine residues that are essential for transforming activity of the ret proto-oncogene with MEN2A or MEN2B mutation. Oncogene 12, 481-7
8637703   Curated Info