Thr382
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Home > Phosphorylation Site Page: > Thr382  -  STK33 (human)

Site Information
LLDNQWLtGNkLSSV   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 25755119

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
HEK293T (epithelial) ( 1 ) , hepatocyte-liver ( 1 )

Upstream Regulation
Regulatory protein:
TTC36 (human) ( 1 )
Putative in vivo kinases:
STK33 (human) ( 1 )
Kinases, in vitro:
STK33 (human) ( 1 )
Treatments:
siRNA ( 1 )

Downstream Regulation
Effects of modification on STK33:
molecular association, regulation ( 1 ) , protein degradation ( 1 ) , ubiquitination ( 1 )
Induce interaction with:
PELI1 (human) ( 1 )

References 

1

Xie Y, et al. (2019) HPD degradation regulated by the TTC36-STK33-PELI1 signaling axis induces tyrosinemia and neurological damage. Nat Commun 10, 4266
31537781   Curated Info