Ser505
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Home > Phosphorylation Site Page: > Ser505  -  EXOC8 (rat)

Site Information
QVFDSKEsLSTAAEC   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 25291117

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mass spectrometry ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
'3T3-L1, differentiated' (adipocyte) ( 1 ) , COS (fibroblast) ( 1 ) , HEK293T (epithelial) ( 1 )

Upstream Regulation
Kinases, in vitro:
TBK1 (rat) ( 1 )

Downstream Regulation
Effects of modification on EXOC8:
molecular association, regulation ( 1 )
Effects of modification on biological processes:
exocytosis, inhibited ( 1 )
Inhibit interaction with:
EXOC8 (rat) ( 1 ) , Sec5 (rat) ( 1 )

References 

1

Uhm M, et al. (2017) Phosphorylation of the exocyst protein Exo84 by TBK1 promotes insulin-stimulated GLUT4 trafficking. Sci Signal 10
28325821   Curated Info

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