Tyr418
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Home > Phosphorylation Site Page: > Tyr418  -  RIP140 (mouse)

Site Information
TPTTIDEySDNNPSF   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 25234800

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:
HEK293T (epithelial) ( 1 ) , macrophage-peritoneum ( 1 ) , RAW 264 (macrophage) ( 1 )

Upstream Regulation
Putative in vivo kinases:
Syk (human) ( 1 )
Kinases, in vitro:
Syk (human) ( 1 )
Treatments:
LPS ( 1 )

Downstream Regulation
Effects of modification on RIP140:
protein degradation ( 1 ) , ubiquitination ( 1 )

References 

1

Ho PC, et al. (2012) NF-κB-mediated degradation of the coactivator RIP140 regulates inflammatory responses and contributes to endotoxin tolerance. Nat Immunol 13, 379-86
22388040   Curated Info

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