Tyr465
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.5.8
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Tyr465  -  Gelsolin (human)

Site Information
VPVDPATyGQFYGGD   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 456958

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 2 )
Disease tissue studied:
liver cancer ( 2 )
Relevant cell line - cell type - tissue:
liver ( 2 )

Upstream Regulation
Kinases, in vitro:
Src (human) ( 3 )

References 

1

Finkelstein M, Megnagi B, Ickowicz D, Breitbart H (2013) Regulation of sperm motility by PIP2(4,5) and actin polymerization. Dev Biol 381, 62-72
23791551   Curated Info

2

Tucker M (2009) CST Curation Set: 7753; Year: 2009; Biosample/Treatment: tissue, liver/untreated; Disease: liver cancer; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info

3

De Corte V, et al. (1999) Identification of Tyr438 as the major in vitro c-Src phosphorylation site in human gelsolin: a mass spectrometric approach. Protein Sci 8, 234-41
10210201   Curated Info