Ser762
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Home > Phosphorylation Site Page: > Ser762  -  EPB41L3 (human)

Site Information
WEkRLstsPVRLAAR   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 456907

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 2 , 3 , 4 , 5 , 7 , 8 , 9 , 10 , 11 , 12 , 13 )
Disease tissue studied:
breast cancer ( 4 ) , lung cancer ( 2 , 4 ) , non-small cell lung cancer ( 4 ) , non-small cell lung adenocarcinoma ( 2 ) , neuroblastoma ( 3 ) , FTLD ( 8 )
Relevant cell line - cell type - tissue:
'brain, cerebral cortex' ( 8 ) , 293 (epithelial) [AT1 (human), transfection, AT1R stable transfected HEK293] ( 9 ) , A498 (renal) ( 10 ) , BT-20 (breast cell) ( 4 ) , BT-549 (breast cell) ( 4 ) , Flp-In T-Rex-293 (epithelial) ( 5 ) , Flp-In T-Rex-293 (epithelial) [PRKD1 (human), genetic knockin] ( 5 ) , H2077 (pulmonary) ( 4 ) , H2887 (pulmonary) ( 4 ) , H322 (pulmonary) ( 4 ) , H322M (pulmonary) ( 4 ) , HCC1359 (pulmonary) ( 4 ) , HCC1937 (breast cell) ( 4 ) , HCC2279 (pulmonary) ( 4 ) , HCC366 (pulmonary) ( 4 ) , HCC4006 (pulmonary) ( 4 ) , HeLa (cervical) ( 13 ) , HOP62 (pulmonary) ( 4 ) , HUES-9 ('stem, embryonic') ( 7 ) , LOU-NH91 (squamous) ( 4 ) , lung ( 2 ) , MCF-7 (breast cell) ( 4 ) , MDA-MB-231 (breast cell) ( 4 ) , MDA-MB-468 (breast cell) ( 4 ) , NB10 (neural crest) ( 3 ) , NCI-H1395 (pulmonary) ( 4 ) , NCI-H1568 (pulmonary) ( 4 ) , NCI-H1648 (pulmonary) ( 4 ) , NCI-H2030 (pulmonary) ( 4 ) , NCI-H2172 (pulmonary) ( 4 ) , NCI-H460 (pulmonary) ( 4 , 11 ) , NCI-H520 (squamous) ( 4 ) , NCI-H647 (pulmonary) ( 4 ) , NPC (neural crest) ( 3 ) , PC9 (pulmonary) ( 4 ) , platelet-blood ( 12 )

References 

1

Boeing S, et al. (2016) Multiomic Analysis of the UV-Induced DNA Damage Response. Cell Rep 15, 1597-1610
27184836   Curated Info

2

Schweppe DK, Rigas JR, Gerber SA (2013) Quantitative phosphoproteomic profiling of human non-small cell lung cancer tumors. J Proteomics 91, 286-96
23911959   Curated Info

3

DeNardo BD, et al. (2013) Quantitative phosphoproteomic analysis identifies activation of the RET and IGF-1R/IR signaling pathways in neuroblastoma. PLoS One 8, e82513
24349301   Curated Info

4

Klammer M, et al. (2012) Phosphosignature predicts dasatinib response in non-small cell lung cancer. Mol Cell Proteomics 11, 651-68
22617229   Curated Info

5

Franz-Wachtel M, et al. (2012) Global detection of protein kinase D-dependent phosphorylation events in nocodazole-treated human cells. Mol Cell Proteomics 11, 160-70
22496350   Curated Info

6

Beli P, et al. (2012) Proteomic Investigations Reveal a Role for RNA Processing Factor THRAP3 in the DNA Damage Response. Mol Cell 46, 212-25
22424773   Curated Info

7

Rigbolt KT, et al. (2011) System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. Sci Signal 4, rs3
21406692   Curated Info

8

Herskowitz JH, et al. (2010) Phosphoproteomic Analysis Reveals Site-Specific Changes in GFAP and NDRG2 Phosphorylation in Frontotemporal Lobar Degeneration. J Proteome Res 9, 6368-79
20886841   Curated Info

9

Christensen GL, et al. (2010) Quantitative phosphoproteomics dissection of seven-transmembrane receptor signaling using full and biased agonists. Mol Cell Proteomics 9, 1540-53
20363803   Curated Info

10

Schreiber TB, et al. (2010) An integrated phosphoproteomics work flow reveals extensive network regulation in early lysophosphatidic acid signaling. Mol Cell Proteomics 9, 1047-62
20071362   Curated Info

11

Nagano K, et al. (2009) Phosphoproteomic analysis of distinct tumor cell lines in response to nocodazole treatment. Proteomics 9, 2861-74
19415658   Curated Info

12

Zahedi RP, et al. (2008) Phosphoproteome of resting human platelets. J Proteome Res 7, 526-34
18088087   Curated Info

13

Beausoleil SA, et al. (2006) A probability-based approach for high-throughput protein phosphorylation analysis and site localization. Nat Biotechnol 24, 1285-92
16964243   Curated Info