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Site Information |
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yNRTRRIsQTsQVsI SwissProt Entrez-Gene |
Blast this site against: NCBI SwissProt PDB |
Site Group ID: 448848 |
In vivo Characterization | |
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Methods used to characterize site in vivo: | |
Relevant cell line - cell type - tissue: |
Upstream Regulation | |
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Regulatory protein: | |
Putative in vivo kinases: | |
Kinases, in vitro: | |
Putative upstream phosphatases: | |
Phosphatases, in vitro: | |
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References | |
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Lee TI, et al. (2023) Ketogenic Diet Regulates Cardiac Remodeling and Calcium Homeostasis in Diabetic Rat Cardiomyopathy. Int J Mol Sci 24
38003332 Curated Info |
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Shuai W, et al. (2023) 5-Methoxytryptophan alleviates atrial structural remodeling in ibrutinib-associated atrial fibrillation. Heliyon 9, e19501
37810107 Curated Info |
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Fender H, et al. (2023) Calcium Handling Remodeling Underlies Impaired Sympathetic Stress Response in Ventricular Myocardium from Haploinsufficient Rats. Int J Mol Sci 24
37372947 Curated Info |
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Xu B, et al. (2022) Probing spatiotemporal PKA activity at the ryanodine receptor and SERCA2a nanodomains in cardomyocytes. Cell Commun Signal 20, 143
36104752 Curated Info |
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Wang YW, et al. (2021) Bay 60-7550, a PDE2 inhibitor, exerts positive inotropic effect of rat heart by increasing PKA-mediated phosphorylation of phospholamban. Eur J Pharmacol 901, 174077
33798601 Curated Info |
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Liu GS, et al. (2015) A novel human R25C-phospholamban mutation is associated with super-inhibition of calcium cycling and ventricular arrhythmia. Cardiovasc Res 107, 164-74
25852082 Curated Info |
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Li J, et al. (2013) ß-Adrenergic Stimulation Increases RyR2 Activity via Intracellular Ca(2+) and Mg(2+) Regulation. PLoS One 8, e58334
23533585 Curated Info |
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Johnsen AB, et al. (2013) Atrial myocyte function and ca(2+) handling is associated with inborn aerobic capacity. PLoS One 8, e76568
24146891 Curated Info |
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Lundby A, et al. (2012) Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues. Nat Commun 3, 876
22673903 Curated Info |
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Tian C, et al. (2011) Gain of function of cardiac ryanodine receptor in a rat model of type 1 diabetes. Cardiovasc Res 91, 300-9
21421556 Curated Info |
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Huke S, Bers DM (2008) Ryanodine receptor phosphorylation at Serine 2030, 2808 and 2814 in rat cardiomyocytes. Biochem Biophys Res Commun 376, 80-5
18755143 Curated Info |
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Ferrero P, et al. (2007) Ca2+/calmodulin kinase II increases ryanodine binding and Ca2+-induced sarcoplasmic reticulum Ca2+ release kinetics during beta-adrenergic stimulation. J Mol Cell Cardiol 43, 281-91
17643448 Curated Info |
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Huke S, Bers DM (2007) Temporal dissociation of frequency-dependent acceleration of relaxation and protein phosphorylation by CaMKII. J Mol Cell Cardiol 42, 590-9
17239900 Curated Info |
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Yang D, et al. (2007) Ca2+/calmodulin kinase II-dependent phosphorylation of ryanodine receptors suppresses Ca2+ sparks and Ca2+ waves in cardiac myocytes. Circ Res 100, 399-407
17234969 Curated Info |