Tyr4
Javascript is not enabled on this browser. This site will not work properly without Javascript.
PhosphoSitePlus Homepage PhosphoSitePlus® v6.5.9.3
Powered by Cell Signaling Technology
Home > Phosphorylation Site Page: > Tyr4  -  syntenin (human)

Site Information
____MsLyPsLEDLk   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 23940700

In vivo Characterization
Methods used to characterize site in vivo:
mass spectrometry ( 1 ) , mutation of modification site ( 2 ) , western blotting ( 2 )
Relevant cell line - cell type - tissue:
HeLa (cervical) ( 1 ) , J774 (macrophage) ( 2 ) , lymphoblastoid ( 2 )

Upstream Regulation
Putative in vivo kinases:
Src (human) ( 2 )
Treatments:
CXCL12 ( 2 ) , PP2 ( 2 )

Downstream Regulation
Effects of modification on syntenin:
molecular association, regulation ( 2 )
Effects of modification on biological processes:
cell motility, induced ( 2 ) , cytoskeletal reorganization ( 2 )
Induce interaction with:
MPRIP (human) ( 2 )

References 

1

Sharma K, et al. (2014) Ultradeep human phosphoproteome reveals a distinct regulatory nature of Tyr and Ser/Thr-based signaling. Cell Rep 8, 1583-94
25159151   Curated Info

2

Sala-Vald├ęs M, et al. (2012) Association of syntenin-1 with M-RIP polarizes Rac-1 activation during chemotaxis and immune interactions. J Cell Sci 125, 1235-46
22349701   Curated Info