Arg239
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Home > Mono-methylation Site Page: > Arg239  -  RIP140 (human)

Site Information
EPLSCAArLQAVASM   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 2363402

In vivo Characterization
Methods used to characterize site in vivo:
immunoprecipitation ( 1 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Disease tissue studied:
testicular cancer ( 1 )
Relevant cell line - cell type - tissue:
'3T3-L1, differentiated' (adipocyte) ( 1 ) , COS (fibroblast) ( 1 ) , E.coli (bacterial) ( 1 ) , MEF (fibroblast) ( 1 ) , P19 (testicular) ( 1 ) , Sf21 ( 1 )

Upstream Regulation
Treatments:
AdOx ( 1 ) , siRNA ( 1 )

Downstream Regulation
Effects of modification on RIP140:
intracellular localization ( 1 ) , molecular association, regulation ( 1 )
Effects of modification on biological processes:
transcription, induced ( 1 )
Induce interaction with:
Exportin-1 (human) ( 1 )
Inhibit interaction with:
DNA ( 1 ) , HDAC3 (human) ( 1 )

References 

1

Mostaqul Huq MD, et al. (2006) Suppression of receptor interacting protein 140 repressive activity by protein arginine methylation. EMBO J 25, 5094-104
17053781   Curated Info

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