Arg407
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Home > Phosphorylation Site Page: > Arg407  -  AR (human)

Site Information
AAAAAQCrYGDLASL   SwissProt Entrez-Gene
Blast this site against: NCBI  SwissProt  PDB 
Site Group ID: 23303205

In vivo Characterization
Methods used to characterize site in vivo:
mutation of modification site ( 1 )
Relevant cell line - cell type - tissue:

Downstream Regulation
Effects of modification on AR:
molecular association, regulation ( 1 ) , protein conformation ( 1 )
Effects of modification on biological processes:
transcription, inhibited ( 1 )

Disease / Diagnostics Relevance
Relevant diseases:
AIS ( 1 )

References 

1

Lagarde WH, et al. (2012) Androgen receptor exon 1 mutation causes androgen insensitivity by creating phosphorylation site and inhibiting melanoma antigen-A11 activation of NH2- and carboxyl-terminal interaction-dependent transactivation. J Biol Chem 287, 10905-15
22334658   Curated Info