Thr603

Site Information
EWLGNENtEDQysLV SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 23131939

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 1 , 2 , 3 )
Disease tissue studied:	gastric cancer ( 2 ) , gastric carcinoma ( 2 )
Relevant cell line - cell type - tissue:	E.coli (bacterial) ( 1 ) , Jurkat (T lymphocyte) ( 3 ) , MKN-45 (gastric) ( 2 )

References
1	Maheshwari S, et al. (2017) Kinetic and structural analyses reveal residues in phosphoinositide 3-kinase α that are critical for catalysis and substrate recognition. J Biol Chem 292, 13541-13550 28676499 Curated Info
2	Moritz A (2011) CST Curation Set: 12369; Year: 2011; Biosample/Treatment: cell line, MKN-45/untreated; Disease: gastric carcinoma; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991 Curated Info
3	Moritz A (2009) CST Curation Set: 8210; Year: 2009; Biosample/Treatment: cell line, Jurkat/pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991 Curated Info