Tyr735

Site Information
LVVPEQEyPLVCVGV SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 23117826

In vivo Characterization
Methods used to characterize site in vivo:	mass spectrometry ( 2 ) , mass spectrometry (in vitro) ( 1 )
Relevant cell line - cell type - tissue:	HEK293T (epithelial) ( 1 ) , Jurkat (T lymphocyte) ( 2 )

Downstream Regulation
Effects of modification on KHS2:	molecular association, regulation ( 1 )
Induce interaction with:	IQGAP1 (human) ( 1 )

References
1	Chuang HC, et al. (2019) MAP4K3/GLK promotes lung cancer metastasis by phosphorylating and activating IQGAP1. Cancer Res 79 31431460 Curated Info
2	Zhou J (2011) CST Curation Set: 12495; Year: 2011; Biosample/Treatment: cell line, Jurkat/calyculin_A & pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991 Curated Info

References

Chuang HC, et al. (2019) MAP4K3/GLK promotes lung cancer metastasis by phosphorylating and activating IQGAP1. Cancer Res 79
31431460 Curated Info

Zhou J (2011) CST Curation Set: 12495; Year: 2011; Biosample/Treatment: cell line, Jurkat/calyculin_A & pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY Antibodies Used to Purify Peptides prior to LCMS: Phospho-Tyrosine Mouse mAb (P-Tyr-100) Cat#: 9411, PTMScan(R) Phospho-Tyr Motif (Y*) Immunoaffinity Beads Cat#: 1991
Curated Info