Tyr86

Site Information
AQEDGKVyINMPGRG SwissProt Entrez-Gene
Blast this site against: NCBI SwissProt PDB
Site Group ID: 23112287

In vivo Characterization
Methods used to characterize site in vivo:	immunoprecipitation ( 1 ) , mass spectrometry ( 2 ) , mutation of modification site ( 1 ) , phospho-antibody ( 1 ) , western blotting ( 1 )
Relevant cell line - cell type - tissue:	A431 (epithelial) ( 1 ) , HaCaT (keratinocyte) ( 1 ) , HEK293T (epithelial) ( 1 ) , Jurkat (T lymphocyte) ( 2 )

Downstream Regulation
Effects of modification on HCST:	intracellular localization ( 1 )

References
1	Sakaguchi M, et al. (2014) DNAX-activating Protein 10 (DAP10) Membrane Adaptor Associates with Receptor for Advanced Glycation End Products (RAGE) and Modulates the RAGE-triggered Signaling Pathway in Human Keratinocytes. J Biol Chem 289, 23389-402 25002577 Curated Info
2	Zhou J (2011) CST Curation Set: 12026; Year: 2011; Biosample/Treatment: cell line, Jurkat/calyculin_A & pervanadate; Disease: T cell leukemia; SILAC: -; Specificities of Antibodies Used to Purify Peptides prior to LCMS: pY(YXXM) Antibodies Used to Purify Peptides prior to LCMS: Phospho-(Tyr) p85 PI3K Binding Motif Antibody Cat#: 3821 Curated Info